[BioMech 07] Evaluation of the tibia strains in order to prevent the astronauts’ osteoporosis
Osteoporosis is a bone disease touching millions of people worldwide that could lead to the break of the bone. Segments of the population more at risk are post-menopausal women and aged people, who are touched by primary osteoporosis. For post-menopausal women, the major cause is the drop in estrogen, a key player in the regulation of bone formation. In aged people, the cause must be mechanical: since bone reacts to muscles activity and force, a reduction in muscle force reduces bone formation too. Other particular conditions can cause rapid bone loss, through secondary osteoporosis. This is, for example, the disuse osteoporosis, which affects disabled people or astronauts.
A sensor, able to measure bone strain, has been already developed and has been used on patients to evaluate the bone deformation during regular exercises.
This master thesis should focus on developing a mesh model of the bone that has been used in the experiment. This model shall be based on a CT-scan made on a patient. The second step shall focus on the evaluation of the bone strain. And the third step shall be dedicated to validate the model based on experiments that will be made according to the needs.